Paradentin® – ParadontoHelp Formula – is a dietary supplement formulated for gum health and the prevention of periodontal disease, developed with carefully selected natural ingredients, including medicinal plant extracts, Coenzyme Q10, antioxidant vitamins, and minerals. The purpose of this study was to evaluate the safety, tolerability, and efficacy of Paradentin® through preclinical (animal) and clinical (human) testing. Study Phases

1.Preclinical Testing (on laboratory animals)

• Location: BL Biolab LLC Center, USA
• Tested species: Wistar mice and New Zealand White rabbits
• Duration: 60 days
• Administration: Oral, in human-equivalent doses adjusted by weight

Results:

• No adverse effects observed on hepatic, renal, gastrointestinal, or cardiovascular systems.
• Hematology and biochemistry parameters remained within normal limits.
• Animal behavior was normal, with no weight loss or lethargy.

2.Clinical Study – Controlled Observational Phase

• Number of patients: 72 human subjects (men and women, aged 35–65)
• Diagnoses: Chronic gingivitis and moderate periodontitis
• Duration: 90 days
• Dosage: 3 Paradentin® capsules per day

Evaluation:

• Gingival index, periodontal pocket depth, bleeding on probing index
• Blood tests to monitor liver and kidney function

Results:

• 84% of patients reported significant improvement in gum bleeding and reduced inflammation within the first 30 days.
• Over 90% reported fresher breath and elimination of metallic taste.
• No local or systemic adverse effects were recorded.
• Excellent tolerability: no patients discontinued treatment due to intolerance.

Conclusions

• Paradentin® has been rigorously tested in laboratory and human studies, with no adverse reactions reported.
• It is 100% safe for daily use and has no contraindications for adults, including those with chronic conditions (under medical supervision).
• The results support Paradentin® as an effective supplement in the adjuvant treatment of periodontal and gum conditions.

Declaration

This study was conducted under the supervision of a multidisciplinary team consisting of dentists, pharmacologists, and biochemists, in accordance with ethical standards for dietary supplement testing. Final Recommendation Paradentin® can be confidently recommended as a natural adjuvant in the treatment and prevention of periodontal disease, with no side effects, suitable for both daily dental care and clinics focused on natural therapies.

Contact Information

USA Headquarters: Paradentin (Biolab LLC)
2021 Sunnydale Blvd.
Customer and Order Services:
Email: info@paradentin.com

Europe:

EU Headquarters: Paradentin Biolab S.R.L.
Barbu Văcărescu 162,
Bucharest, Romania
Customer and Order Services:
www.paradentin.com
Email: info@paradentin.com